ea0099p252 | Calcium and Bone | ECE2024
Carrara Silvia
, Vai Silvia
, Mihalich Alessandra
, Blasio Anna Di
, Ponti Emanuela
, Guabello Gregorio
, Guarnieri Vito
, Pigni Stella
, Lania Andrea
, Mazziotti Gherardo
, Corbetta Sabrina
Osteoporosis causes bone fragility usually affecting the elderly. Genetic susceptibility plays a crucial role in determining the risk of fragility fractures and is involved in early-onset osteoporosis. When fragility fractures or low bone mineral density (BMD) occur in young adults without evident secondary osteoporosis, an underlying monogenetic bone disease should be assessed. The list of genes related to low BMD and their mutations is increasing. Nevertheless, little is kno...